Publisher review:Melting program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA.
The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easely changed, for instance following an experimental breakthrough.
Melting 4.2g is a C/C++ script for Chat Scripts scripts design by Nicolas Le Novere.
It runs on following operating system: Windows / Linux / Mac OS / BSD / Solaris.
Melting program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions.
Operating system:Windows / Linux / Mac OS / BSD / Solaris